Importancia del informe del uroproteinograma

Abstract

Urinary protein electrophoresis is a qualitative assessment of the composition of protein in the urine. This study complements the quantitative examination, can identify the nature of the proteins and can differentiate the type of proteinuria. This allows the physician an appropriate diagnosis, treatment and follow-up of kidney disease. The objective of this paper is to show through a clinic case a difference between a descriptive urinary protein electrophoresis report or typifying the proteinuria. Clinic case: male of one year and two months old with bad somatic progress, polydipsia and normal neurological development. An urinary electrophoresis with a proteinuria of 2.3 g / l and a narrative report: discrete Albumin , beta , alpha and alpha one area two faint bands in gamma area. Report that does not allow the Nephrologist define the type of proteinuria. In our laboratory was performed on agarose gel an urinary protein electrophoresis with a technique developed in house. Immunofixation with specific antisera (anti-GAM-anti- Kappa-anti-Lambda- anti-tubular -anti-post Renal) and staining with acid violet. Polyacrylamide gel electrophoresis with sodium dodecyl sulphate in concentratedand unconcentrated urine. As a conclusion we can say that urinary protein electrophoresis should be performed by qualified personnel in the field, to properly define the type of proteinuria